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Aaron Leconte – Chemistry

Professor Leconte and his research group published the article:

  • “Mutant polymerases capable of 2鈥 fluoro-modified nucleic acid synthesis and amplification with improved accuracy鈥 in聽Royal Society of Chemistry – Chemical Biology. 聽This work was executed and co-authored in its entirety by four Keck Science Department undergraduates: Trevor Christensen (CMC聽鈥22), Kristi Lee (SCR聽鈥20), Simone Gottlieb (SCR聽鈥21) and Mikayla Carrier (SCR聽鈥21). 聽In the work, they describe new methods for making the synthesis of unnatural forms of DNA more accurate. 聽This work has implications for the use of unnatural DNA in medicine and disease diagnostics.

Link:

Full citation: T.A. Christensen, K.Y. Lee, S.Z.P. Gottlieb, M.B. Carrier, and A.M Leconte (2022). Mutant polymerases capable of 2鈥檉luoro-modified nucleic acid synthesis and amplification with improved accuracy, RSC Chemical Biology, 3, 1044.

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